Yazar "Alan, Saadet" için listeleme
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Combination therapy with chitosan/siRNA nanoplexes targeting PDGF-D and PDGFR-beta reveals anticancer effect in breast cancer
Şalva, Emine; Özbaş, Suna; Alan, Saadet; Özkan, Naziye; Ekentok Atıcı, Ceyda; Kabasakal, Levent; Akbuğa, Jülide (Wiley, 2023)Background: Platelet derived growth factors (PDGF)-D and the expression of its receptor increase in neoplastic progression of cancer. Co-silencing of growth factor and receptor can be suggested as an important strategy for ... -
Evaluation of the effect of honey-containing chitosan/hyaluronic acid hydrogels on wound healing
Şalva, Emine; Akdağ, Ahmet Enes; Alan, Saadet; Arısoy, Sema; Akbuğa, Fatma Jülide (Multidisciplinary Digital Publishing Institute (MDPI), 2023)The 3D polymeric network structure of hydrogels imitates the extracellular matrix, thereby facilitating cell growth and differentiation. In the current study, chitosan/hyaluronic acid/honey coacervate hydrogels were produced ... -
Investigation of therapeutic effects in the wound healing of chitosan/pGM-CSF complexes
Şalva, Emine; Alan, Saadet; Karakoyun, Berna; Çakalağaoğlu, Fulya; Özbaş, Suna; Akbuğa, Jülide (Universidade de São Paulo, 2022)Granulocyte macrophage colony-stimulating factor (GM-CSF) has been shown to promote the growth, proliferation, and migration of endothelial and keratinocyte cells. Chitosan has been widely used as a biopolymer in wound-healing ...